Motilin Receptor Agonist
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Motilin (26-47), human, porcine
0 ImagesCat. No.: HY-P1037CAS No.: 52906-92-0Motilin (26-47), human, porcine is an endogenous motilin receptor ligand with Ki and EC50 of 2.3 nM and 0.3 nM in a Chinese hamster ovary cell line.
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DS-3801b
0 ImagesDS-3801b is a potent and non-macrolide agonist of GPR38. DS-3801b is expected to be novel gastrointestinal prokinetic agents for the research of functional gastrointestinal disorders such as gastroparesis and chronic constipation.
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KC-11458
0 ImagesCat. No.: HY-105333CAS No.: 151052-43-6KC-11458 is a motilin agonist. KC-11458 can accelerate gastric emptying.
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[Leu13]-Motilin
![[Leu13]-Motilin](https://file.medchemexpress.com/product_pic/hy-106323.gif "Click to View [Leu13]-Motilin Product Detail")
0 ImagesCat. No.: HY-106323CAS No.: 59530-69-7Synonyms: KW-5139[Leu13]-Motilin (KW-5139) is a motilin analogue. [Leu13]-Motilin stimulates gastrointestinal motility in the rabbit. [Leu13]-Motilin causes concentration-dependent contractions of the gastric antrum, duodenum, jejunum, ileum and the descending colon in vitro.
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Mitemcinal fumarate
0 ImagesCat. No.: HY-106018ACAS No.: 154802-96-7Synonyms: GM 611 fumarateMitemcinal fumarate is an oral motilium agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal fumarate may be a constipation suppressant due to its early onset and short duration of action.
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EM-523
0 ImagesCat. No.: HY-106327CAS No.: 110205-60-2EM-523 is a motilin agonist and an erythromycin derivative. EM-523 has pED50 values of 8.19 and 6.08 for promoting contractions in rabbit small intestinal tissue and human duodenal tissue, respectively. EM-523 can be used in the research of gastrointestinal diseases.
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Mitemcinal
0 ImagesCat. No.: HY-106018CAS No.: 154738-42-8Synonyms: GM 611Mitemcinal (GM 611) is an oral motilin receptor agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal may be a constipation suppressant due to its early onset and short duration of action.
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EM574
0 ImagesCat. No.: HY-105263CAS No.: 110480-13-2EM574 is a potent motilin receptor agonist in the human gastric antrum and rabbit gastrointestinal tract in vitro. EM574 is an erythromycin derivative.
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[Nle13]-Motilin
![[Nle13]-Motilin](https://file.medchemexpress.com/product_pic/hy-p3680.gif "Click to View [Nle13]-Motilin Product Detail")
0 ImagesCat. No.: HY-P3680CAS No.: 55524-56-6[Nle13]-Motilin, a motilin analogue, is a motilin receptor agonist.
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Atilmotin
0 ImagesCat. No.: HY-106258CAS No.: 533927-56-9Synonyms: OHM 11638; BAX-ACC 1638; MOT 288OHM 11638 (Atilmotin), an analogue of the (1-14) fragment of porcine motilin, is a motilin receptor agonist with a pKd of 8.94 for the motilin receptor. OHM 11638 affects esophageal, lower esophageal sphincter (LES), and gastric motility. OHM 11638 increases LES and gastric pressures, OHM 11638 can be used as prokinetic agents.
